Ghana midfielder Emmanuel Frimpong has suffered a fresh injury setback as he has been ruled out for an estimated period of two months with a knee injury, meaning he will not be available for the Black Stars in next month’s 2014 World Cup qualifiers.

The new Ghana international underwent successful surgery on Wednesday to fix the injury.

The 21-year-old was said to have suffered the injury while with Fulham where he spent the remaining half of Premier League season on loan.

This is the second major knee operation Frimpong has undergone.

Injuries to Victor Moses and Kalu Uche have left Nigeria short of attackers for June's World Cup qualifiers and the Confederations Cup in Brazil.

The pair's withdrawal from the squad deepens problems for coach Stephen Keshi, who was already without Nations Cup joint-top scorer Emmanuel Emenike.

Keshi said: "It's unfortunate that they informed us when we have already finalised our provisional squad.

"It is now too late to start calling up replacement players."

English Premier League side Chelsea informed Nigeria that Moses requires treatment for a recurring injury, while Kalu Uche said he has played with an injury throughout the season in Turkey and, on the advice of his doctor, will be using the off-season to undergo treatment.

Zambia international defender Stoppila Sunzu has successfully undergone arthroscopic knee surgery.

Sunzu was operated on under the watchful eye of the Chipolopolo Team Doctor at the Italian Orthopaedic Hospital in Lusaka last week Friday.

Following the operation, the defender now needs complete rest to fully recover. He is expected to be off all training for a minimum of four weeks.

During his period of recovery, the Zambia national team head of medical Dr Joseph Kabungo will continue monitoring the player’s progress.

Ghana defender Isaac Vorsah’s injury has proved serious than initially feared as tests have shown suffered two injuries and will be out of six months.

The Austria based centre-back will be out of action until October and he will miss three key World Cup qualifiers for the Black Stars.

It was thought the Red Bull Salzburg defender suffered a suspected cruciate ligament injury when he was substituted during Tuesday Austrian FA Cup match.

But MRI scans conducted on the Ghana international have also shown that he pulled a collateral ligament ruling him out of action for six months.

Manchester City midfielder Yaya Toure has declared himself fully fit to face Wigan in Saturday's FA Cup final.

The Ivorian played only 45 minutes of Saturday's Premier League draw with Swansea because of fatigue and also sat out the midweek win over West Brom.

"Sometimes it is difficult to play all the games at the same level and to avoid injury," said the 29-year-old.

"But we have worked on ensuring I stay injury-free and concentrated on delivering at the weekend."

Ivory Coast goalkeeper Copa Barry was discharged from a Belgian hospital on Tuesday after he was rushed there from a stadium during the weekend’s league match between his side Lokeren and FC Bruges.

The 33-year-old crashed against one of his posts while trying to save a ball and lost consciousness for several minutes before being evacuated to the nearest hospital.

A medical report said Copa suffered a brief concussion but was now doing fine. However, he would stay off the pitch for at least a week, the club’s medical staff said.

Copa is Ivory Coast first choice goalkeeper and the news sent shock waves across the West African nation last weekend, as the Elephants gear up for their trip to Gambia in the 2014 Fifa World Cup qualifying.

Nigeria striker Emmanuel Emenike underwent knee surgery on Thursday and will be out for six weeks.

It means the 25-year-old, who was joint top scorer at this year's Africa Cup of Nations, will miss World Cup qualifiers against Kenya and Namibia next month.

"Emenike underwent a successful operation on his meniscus and will miss four to six weeks," his Russian club Spartak Moscow said on their website.

The forward will miss the last four games of the season in Russia.

His absence will be most keenly felt by the Super Eagles, who are level on points with Malawi at the top of their World Cup Group F.

Nigeria striker Emmanuel Emenike will miss June's 2014 World Cup qualifiers and the Fifa Confederations Cup due to a knee injury.

The 25-year-old Spartak Moscow picked up the injury on Sunday, on his return from a long-term hamstring layoff, during a Russian Premier League match.

His club have confirmed that Emenike will be out of action for two months.

"It's a terrible setback for me because I was very happy to be back playing again on Sunday," he told BBC Sport.

"I know injury is part of football but sometimes you struggle to understand why it happens so soon again after recovering.

Zambia’s medical bench expect Stopilla Sunzu's knee to fully heal by mid-May in time for the June’s 2014 qualifiers.

The defender has been struggling with a knee problem for since the end of 2012 that has seen him play at half capacity in Zambia's last four competitive games this year.

Zambia team Doctor Joseph Kabungo told MTNFootball.com in Lusaka that the medical team has placed Sunzu on a special recovery programme.

"His knee is very stable indeed but as you know the stability of the knee relies on a lot of factors and one of the factors is good muscle strength," Dr Kabungo said.

Nigeria striker Joseph Akpala is back in training with German club Werder Bremen after he was out for seven weeks with a left knee injury.

Akpala suffered a ligament tear injury in training in March, which meant he would be sidelined for at least a month and half.

The Jos-born star returned to Bremen on Sunday from Belgium, where he has gone for his rehabilitation.

He trained on his own on Monday with the physical trainer Reinhard Schnittker.

"I went through a rehab programme in Belgium. Now I can work on individual elements on the pitch," Akpala told the Werder Bremen official website.