Manchester City star Yaya Toure was on target for the third time in five English Premier League games this season as he helped his side to a 4:1 trouncing of city rivals Manchester United on Sunday.
It was also the reigning African Footballer of the Year's second goal in successive matches after scoring in a 3:0 win at Viktoria Plzen in the UEFA Champion League on Tuesday.
Argentina striker Sergio Aguero netted a brace - including a stunning volley that opened the floodgates in the 16th minute.
Yaya, who ran the midfield for the hosts in his usual dominant fashion, made it 2:0 from close range just before the break.
Young Cote d'Ivoire striker Wilfried Bony kept up his superb post-AFCON scoring form with his eighth league goal in five games.
His 63rd minute effort gave Vitesse Arnhem a 1:0 win over hosts FC Twente in the Dutch top-flight on Sunday.
The result keeps Vitesse in fourth place just three points behind leaders Ajax Amsterdam.
The 24-year-old was a fringe player in the Elephants' disappointing AFCON campaign, but scored in his only start - a 2:2 draw with Algeria in the group stage.
Also on target in Holland was Zambia striker Jacob Mulenga. The 29-year-old's goal on 78 minutes also gave his side FC Utrecht a 1:0 win over visitors RKC Waalwijk.
Mame Biram Diouf
Michael Essien scored his first goal for Real Madrid since his loan move from Chelsea. The Ghanaian midfielder returned to his favoured position after covering at left-back in recent times. An increasingly important player for coach Jose Mourinho, the versatile Essien was the main organiser and helped control midfield against Zaragoza, bursting through in the final minutes to score in the 4-0 win.
Senegal international Papakouli Diop's performances in midfield have contributed to Levante's recent excellent form. Building on better movement in the past weeks he produced a solid display in front of the defence against Sevilla and helped cut out the threat from the home side's attack. Levante earned a 0-0 draw.
Cote d'Ivoire winger Gervinho shone for Arsenal in a makeshift centre-forward role, scoring twice as they beat visitors Southampton 6:1 in the English Premier League on Saturday.
The Ivorian winger, who had not scored a league in 2012, put in a magnificent shift for the Gunners after filling in for French star Olivier Giroud in attack.
Gervinho hammered home a fine effort in the 35th minute to make it 3:0 Arsenal after he was picked out by Spanish team-mate Mikel Arteta.
An own goal and a Lukas Podolski strike had given the hosts a double cushion, while another own goal made it four zero before the break.